5-(dihydroxyboranyl)-2-methylanilinium chloride

5-(dihydroxyboranyl)-2-methylanilinium chloride - Names and Identifiers

Name	(3-Amino-4-methylphenyl)boronic acid, hydrochloride
Synonyms	3-Amino-p-tolylboronicacid 3-Amino-4-methylphenylboronic 3-AMINO-4-METHYLPHENYLBORONIC ACID 3-AMINO-4-METHYLBENZENEBORONIC ACID 3-Amino-4-methylbenzeneboronic acid (3-amino-4-methylphenyl)boronic acid (3-AMINO-4-METHYLPHENYL)BORONIC ACID, HCL 5-(dihydroxyboranyl)-2-methylanilinium chloride 3-AMINO-4-METHYLPHENYLBORONIC ACID HYDROCHLORIDE 3-Amino-4-methylphenylboronic acid hydrochloride 3-Amino-4-Methylphenylboronic Acid Hydrochloride (3-Amino-4-methylphenyl)boronic acid, hydrochloride 3-AMINO-4-METHYLPHENYLBORONIC ACID HYDROCHLORNIC ACID 3-Amino-4-methylphenylboronic acid~3-Amino-p-tolylboronic acid
CAS	22237-12-3
EINECS	681-828-5
InChI	InChI=1/C7H10BNO2/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,10-11H,9H2,1H3

5-(dihydroxyboranyl)-2-methylanilinium chloride - Physico-chemical Properties

Molecular Formula	C7H10BNO2
Molar Mass	150.97
Density	1.19±0.1 g/cm3(Predicted)
Melting Point	250°C
Boling Point	367.6±52.0 °C(Predicted)
Flash Point	176.1°C
Vapor Presure	4.73E-06mmHg at 25°C
pKa	8.77±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.569
MDL	MFCD01074640

5-(dihydroxyboranyl)-2-methylanilinium chloride - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29310095
Hazard Class	IRRITANT

5-(dihydroxyboranyl)-2-methylanilinium chloride - Introduction

(3-Amino-4-methylphenyl)boronic acid, hydrochloride is an organic compound with the chemical formula C7H10BNO2 and a molecular weight of 154.97g/mol. It had the appearance of a white crystalline solid.

The following is a detailed description of the nature, use, preparation and safety information of (3-Amino-4-methylphenyl)boronic acid, hydrochloride:

1. Nature:
-Appearance: White crystalline solid
-Melting Point: about 145-147 ℃
-Solubility: can be dissolved in some organic solvents, such as alcohols and DMSO, slightly dissolved in water
-Stability: stable at room temperature, but may decompose when heated or damp

2. Use:
-chemical synthesis:(3-Amino-4-methylphenyl)boronic acid, hydrochloride is an important intermediate of organic boron compounds, which is commonly used in C- C bond formation reactions, such as etherification, enolization and oxygen heterocycle reaction.
-Drug research: It is also used in the field of drug synthesis and organometallic chemistry research.

3. Preparation method:
The synthesis of (3-Amino-4-methylphenyl)boronic acid, hydrochloride can be carried out by the following steps:
-First, 2-methylphenylboronic acid and hydrochloric acid are reacted to form 2-methylphenylboronic acid hydrochloride.
-Then, 2-methylphenylboronic acid hydrochloride is reacted with ammonia or propylamine to prepare (3-Amino-4-methylphenyl)boronic acid, hydrochloride hydrochloride.
-Finally, (3-Amino-4-methylphenyl)boronic acid, hydrochloride is subjected to alkali treatment or hydrochloric acid treatment to obtain (3-Amino-4-methylphenyl)boronic acid, hydrochloride.

4. Safety Information:
(3-Amino-4-methylphenyl)boronic acid, hydrochloride has low toxicity, but it is still necessary to pay attention to safe use. Inhalation of dust or contact with skin and eyes should be avoided. Use protective gloves, goggles, and protective clothing when handling this compound. At the same time, it should be operated in a well-ventilated place and avoid contact with oxidants. If waste is to be disposed of, it should be disposed of in accordance with local regulations.

Last Update：2024-04-09 21:11:58